Seth Irunsewe Kale MBE, OON, CFR (June 6, 1904 – November 19, 1994) was a Nigerian Anglican bishop who served as Principal of CMS Grammar School, Lagos from 1944 to 1950 and as Bishop of Lagos from 1963 to 1974.[
He was consecrated a bishop on St Andrew's Day (30 November) 1963, by Cecil Patterson, Archbishop of West Africa.